abstract：BACKGROUND:Previous analyses of real-life data indicated that injection frequency and health care costs did not differ for anti-VEGF treatment with aflibercept and ranibizumab. The objective of this study was to investigate whether this finding persisted when analysing a longer time period after licensing. METHODS:Ret...

journal_title：BMC ophthalmology

authors： Reich O,Schmid MK,Rapold R,Bachmann LM,Blozik E

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Retinal tears complicating the course of a posterior vitreous detachment (PVD) may be unique or multiple, and when multiple they may occur simultaneously or subsequently at different moments in the evolution of a PVD. The purpose of our study was to analyze the prevalence of subsequent retinal tears (SRT) in...

journal_title：BMC ophthalmology

authors： Crim N,Esposito E,Monti R,Correa LJ,Serra HM,Urrets-Zavalia JA

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The aim of the study is to investigate risk factors for future falls in subject with primary open angle glaucoma (POAG). METHODS:All participants answered the following question at their baseline ophthalmic examination: Have you had any falls in the last year? (Yes/No). All study participants answered the s...

journal_title：BMC ophthalmology

authors： Adachi S,Yuki K,Awano-Tanabe S,Ono T,Murata H,Asaoka R,Tsubota K

更新日期：2017-11-25 00:00:00

abstract：BACKGROUND:We present a case of post-traumatic endophthalmitis with relatively good prognosis caused by Gordonia sputi, which, to our knowledge is the first case in the literature. CASE PRESENTATION:A 24 year old man, who underwent an intraocular foreign body extraction half a month before presentation in the left eye...

journal_title：BMC ophthalmology

authors： Fang W,Li J,Cui HS,Jin X,Zhai J,Dai Y,Li Y

更新日期：2017-10-11 00:00:00

abstract：BACKGROUND:This study compared the postoperative outcomes of 27-gauge (G) and 25-G vitrectomy performed for the treatment of idiopathic epiretinal membrane (ERM). METHODS:The study design was single center, retrospective, interventional case series. Two hundred consecutive eyes that underwent primary vitrectomy for ER...

journal_title：BMC ophthalmology

authors： Naruse S,Shimada H,Mori R

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:To analyse the associated factors, diagnosis, clinical manifestations and therapeutic effects of Acanthamoeba keratitis at a tertiary ophthalmic centre in Southern China. METHODS:A retrospective clinical study was performed in fifteen patients who were admitted to Zhongshan Ophthalmic Centre (ZOC) from Janu...

journal_title：BMC ophthalmology

authors： Zhong J,Li X,Deng Y,Chen L,Zhou S,Huang W,Lin S,Yuan J

更新日期：2017-10-02 00:00:00

abstract：BACKGROUND:Myopic foveoschisis (MF) is among the leading causes of visual loss in high myopia. However, it remains controversial whether internal limiting membrane (ILM) peeling or gas tamponade is necessary treatment option for MF. METHODS:PubMed, EMBASE, CBM, CNKI, WANFANG DATA and VIP databases were systematically ...

journal_title：BMC ophthalmology

authors： Meng B,Zhao L,Yin Y,Li H,Wang X,Yang X,You R,Wang J,Zhang Y,Wang H,Du R,Wang N,Zhan S,Wang Y

更新日期：2017-09-08 00:00:00

abstract：BACKGROUND:Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is to identify association between socioeconomic status and the visual impairments caused by primary glaucoma in Korea. METHODS:This study is based on a ...

journal_title：BMC ophthalmology

authors： Sung H,Shin HH,Baek Y,Kim GA,Koh JS,Park EC,Shin J

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:The effects of preservatives of antiglaucoma medications on corneal surface and tear function have been widely shown in literature; it's not the same as regards the active compounds themselves. The purpose of our study was to compare Ocular Surface Disease (OSD) signs and symptoms of Tafluprost 0.0015% versu...

journal_title：BMC ophthalmology

authors： Rolle T,Spinetta R,Nuzzi R

更新日期：2017-08-03 00:00:00

abstract：BACKGROUND:To present a case of conjunctival lymphoma in a young woman complicated by pregnancy. CASE PRESENTATION:A 38-year-old previously healthy woman presented with a 2-year history of progressive right blepharoptosis. Giant papillomatous sessile masses were identified in the upper and lower fornix bilaterally and...

journal_title：BMC ophthalmology

authors： Ong SJ,Jung SM,Lin HC

更新日期：2017-07-27 00:00:00

abstract：BACKGROUND:The purpose of this study is to determine whether the lifestyle and body stature are significantly associated with the axial length (AL) of the eyes of Japanese third grade students. METHODS:A prospective, cross sectional, observational study was performed on 122 third grade students consisting of 61 boys a...

journal_title：BMC ophthalmology

authors： Terasaki H,Yamashita T,Yoshihara N,Kii Y,Sakamoto T

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:This study evaluates patients with congenital aniridia and cataract who underwent phacoemulsification, capsular tension ring placement, and foldable intraocular lens implantation. METHODS:In this prospective case series, 10 patients (17 eyes) underwent cataract surgery via a 3.2 mm clear corneal incision. A...

journal_title：BMC ophthalmology

authors： Wang JD,Zhang JS,Xiong Y,Li J,Li XX,Liu X,Zhao J,Tsai FF,Vishal J,You QS,Huang Y,Wan XH

更新日期：2017-07-04 00:00:00

abstract：BACKGROUND:The gold standard treatments in amblyopia are penalizing therapies, such as patching or blurring vision with atropine that are aimed at forcing the use of the amblyopic eye. However, in the last years, new therapies are being developed and validated, such as dichoptic visual training, aimed at stimulating th...

journal_title：BMC ophthalmology

authors： Žiak P,Holm A,Halička J,Mojžiš P,Piñero DP

更新日期：2017-06-28 00:00:00

abstract：BACKGROUND:Physical cooling of the eye surface relieves ocular discomfort, but translating this event to drug treatment of dry eye discomfort not been studied. Here, we synthesized a water-soluble TRPM8 receptor agonist called cryosim-3 (C3, 1-diisopropylphosphorylnonane) which selectively activates TRPM8 (linked to co...

journal_title：BMC ophthalmology

authors： Yang JM,Li F,Liu Q,Rüedi M,Wei ET,Lentsman M,Lee HS,Choi W,Kim SJ,Yoon KC

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:The aim of this study was to compare superior and temporal clear corneal incisions of uneventful phacoemulsification and in-the-bag intraocular lens implantation on intraocular pressure control and the bleb morphology in eyes that have undergone previous successful trabeculectomy. METHODS:In this Prospectiv...

journal_title：BMC ophthalmology

authors： Anbar M,Ammar H

更新日期：2017-06-26 00:00:00

abstract：BACKGROUND:To describe the characteristics of patients with syphilitic uveitis in northern China. METHODS:A case series of 21 patients (33 eyes) diagnosed with syphilitic uveitis from 2011 to 2016 at a tertiary center in northern China was retrospectively analyzed. RESULTS:Twenty-one patients (33 eyes) were diagnosed...

journal_title：BMC ophthalmology

authors： Zhang X,Du Q,Ma F,Lu Y,Wang M,Li X

更新日期：2017-06-19 00:00:00

abstract：BACKGROUND:To evaluate the efficacy and safety of intravitreal conbercept (KH902) as the primary treatment of choroidal neovascularization secondary to punctate inner choroidopathy. METHODS:This study was a retrospective, consecutive, observational case series. We reviewed medical records of 16 eyes (16 patients) with...

journal_title：BMC ophthalmology

authors： Peng Y,Zhang X,Mi L,Liu B,Zuo C,Li M,Wen F

更新日期：2017-06-12 00:00:00

abstract：BACKGROUND:Congenital cataract is the most frequent cause of blindness during infancy or early childhood. To date, more than 40 loci associated with congenital cataract have been identified, including at least 26 genes on different chromosomes associated with inherited cataract. This present study aimed to identify the...

journal_title：BMC ophthalmology

authors： Shen C,Wang J,Wu X,Wang F,Liu Y,Guo X,Zhang L,Cao Y,Cao X,Ma H

更新日期：2017-05-19 00:00:00

abstract：BACKGROUND:To report patients with age-related macular degeneration and atypical central retinal pigment epithelium (RPE) defects not attributable to geographic atrophy (GA) or RPE-tears with overlying preserved photoreceptor layers. METHODS:Multimodal imaging case-series evaluating the course of atypical RPE- defects...

journal_title：BMC ophthalmology

authors： Giannakaki-Zimmermann H,Querques G,Munch IC,Shroff D,Sarraf D,Chen X,Cunha-Souza E,Mrejen S,Capuano V,Rodrigues MW,Gupta C,Ebneter A,Zinkernagel MS,Munk MR

更新日期：2017-05-15 00:00:00

abstract：BACKGROUND:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening conditions that initially affect the skin and mucous membranes. The aim of this study was to compare the acute ocular manifestations between SJS and TEN. METHODS:The initial presenting ophthalmic records of pat...

journal_title：BMC ophthalmology

authors： Chow LLW,Shih KC,Chan JCY,Lai JSM,Ng ALK

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:To report six cases of CD34+ fibroblastic mesenchymal tumours, which are uncommon neoplasms in the orbit. CASE PRESENTATION:Six patients presenting with proptosis and palpable mass who were later diagnosed with fibrous solitary tumours, fibrous histocytoma or haemangiopericytoma in the orbit were included. ...

journal_title：BMC ophthalmology

authors： Jung SK,Paik JS,Park GS,Yang SW

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:The short-term effects of intravitreal ranibizumab (IVR) on diabetic macular edema (DME) remains unclear. We assessed the short-term effects of IVR on DME. METHODS:Eighteen eyes of 14 patients with DME were enrolled in this prospective interventional case series. After intravitreal ranibizumab was injected ...

journal_title：BMC ophthalmology

authors： Minami Y,Nagaoka T,Ishibazawa A,Yoshida A

更新日期：2017-03-14 00:00:00

abstract：BACKGROUND:Iridoschisis is a rare condition that is characterized by the separation of the iris stroma into layers, with portions of the anterior layer floating freely in the aqueous humour. Here, we report three cases of iridoschisis that were complicated by either a cataract or glaucoma. Based on these cases, we spec...

journal_title：BMC ophthalmology

authors： Chen Y,Qian Y,Lu P

更新日期：2017-03-14 00:00:00

abstract：BACKGROUND:Surgeons may be unaware of the ability of plant toxins to cause corneal damage. Therefore, corneal damage following intraocular surgery due to plant toxins may be misdiagnosed as postoperative infection. CASE PRESENTATION:A 74-year-old man presented with hyperemia and reduced visual acuity in both eyes 6 we...

journal_title：BMC ophthalmology

authors： Matsuura K,Hatta S,Terasaka Y,Inoue Y

更新日期：2017-01-18 00:00:00

abstract：BACKGROUND:To compare corneal hysteresis (CH) measurements between patients with glaucoma, ocular hypertension (OHT) and glaucoma-like optic discs (GLD)- defined as a cup to disc ratio greater than or equal to 0.6 with normal intraocular pressure (IOP) and visual fields. The secondary aim was to investigate whether cor...

journal_title：BMC ophthalmology

authors： Murphy ML,Pokrovskaya O,Galligan M,O'Brien C

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Ocular signs of Fabry disease can be seen in the first decade of life. METHODS:We examined the occurrence of ocular signs in 232 paediatric patients in the Fabry Outcome Survey (FOS) international registry and looked for relationships between the presence of eye findings and disease severity as measured by ...

journal_title：BMC ophthalmology

authors： Kalkum G,Pitz S,Karabul N,Beck M,Pintos-Morell G,Parini R,Rohrbach M,Bizjajeva S,Ramaswami U

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Refractive errors, strabismus, nystagmus, amblyopia, and cortical visual impairment are observed in 50 to 90 % of patients with cerebral palsy. Ocular abnormalities are known to differ according to cerebral palsy type, and spastic type has been reported to be more likely to be associated with ocular defects ...

journal_title：BMC ophthalmology

authors： Park MJ,Yoo YJ,Chung CY,Hwang JM

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:The repertoire of free-living protozoa in contact lens solutions is poorly known despite the fact that such protozoa may act as direct pathogens and may harbor intra-cellular pathogens. METHODS:Between 2009 and 2014, the contact lens solutions collected from patients presenting at our Ophthalmology Departme...

journal_title：BMC ophthalmology

authors： Bouchoucha I,Aziz A,Hoffart L,Drancourt M

更新日期：2016-10-29 00:00:00

abstract：BACKGROUND:To study the value and safety of aqueous humor polymerase chain reaction (PCR) analysis for Herpes simplex, varicella zoster, cytomegalovirus, Epstein-Barr virus and Toxoplasma gondii in patients with uveitis. METHODS:Records of 45 consecutive patients with anterior and posterior uveitis who underwent AC pa...

journal_title：BMC ophthalmology

authors： Chronopoulos A,Roquelaure D,Souteyrand G,Seebach JD,Schutz JS,Thumann G

更新日期：2016-10-28 00:00:00

abstract：BACKGROUND:This is the third reported case of a steatocystoma simplex in the lacrimal caruncle. CASE PRESENTATION:A 60-year-old male presented with a history of a slowly progressing mass in the right lacrimal caruncle since several years before his initial visit. At the first examination, a yellowish, relatively smoot...

journal_title：BMC ophthalmology

authors： Ishida Y,Takahashi Y,Takahashi E,Kitaguchi Y,Kakizaki H

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in healthy adults with isometropia, using enhanced depth imaging optical coherence tomography (EDI SD-OCT)...

journal_title：BMC ophthalmology

authors： Yang M,Wang W,Xu Q,Tan S,Wei S

更新日期：2016-10-19 00:00:00

abstract：BACKGROUND:To determine the most effective route of administration of corticosteroids in the treatment of ocular surface disease, by characterizing the difference between oral prednisolone and topical dexamethasone administration using an animal model. METHODS:Pharmacokinetic analyses determined the corticosteroid con...

journal_title：BMC ophthalmology

authors： Araki-Sasaki K,Katsuta O,Mano H,Nagano T,Nakamura M

更新日期：2016-09-05 00:00:00

abstract：BACKGROUND:Reports of central corneal thickness (CCT) among glaucoma patients, particularly for pseudoexfoliative glaucoma (PXG) and Primary Angle Closure Glaucoma (PACG) are scarce in the Sub-Saharan African (SSA) population. The aim of this study is to evaluate CCT in black patients with newly diagnosed glaucoma and ...

journal_title：BMC ophthalmology

authors： Tolesa K,Gessesse GW

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:Refraction change of silicone oil (SO) tamponade in phakic and aphakic eye has been studied thoroughly; however, it is rarely studied in pseudophakic eye. In this paper we aimed to deduce a theoretical formula predicting refractive shift of silicone oil tamponade in pseudophakic eye and compared it with clin...

journal_title：BMC ophthalmology

authors： Fang W,Li J,Jin X,Zhai J,Dai Y,Li Y

更新日期：2016-08-16 00:00:00

abstract：BACKGROUND:Patient education materials should be written at a level that is understandable for patients with low health literacy. The aims of this study are (1) to review the literature on readability of ophthalmic patient education materials and (2) to evaluate and revise our institution's patient education materials ...

journal_title：BMC ophthalmology

authors： Williams AM,Muir KW,Rosdahl JA

更新日期：2016-08-03 00:00:00

abstract：BACKGROUND:Optical coherence tomography angiography is a novel imaging technique that allows dyeless in vivo visualization of the retinal and choroidal vasculature. The purpose of this study was to describe optical coherence tomography (OCT) angiography findings in patients with retinal arterial macroaneurysms (RAMs). ...

journal_title：BMC ophthalmology

authors： Alnawaiseh M,Schubert F,Nelis P,Wirths G,Rosentreter A,Eter N

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in ...

journal_title：BMC ophthalmology

authors： Tokimitsu M,Murata M,Toriyama Y,Hirano T,Iesato Y,Murata T

更新日期：2016-07-19 00:00:00

abstract：BACKGROUND:The ocular presentation of Castleman's disease (CD)-associated paraneoplastic pemphigus (PNP) has rarely been reported. In this report, we describe a young patient with CD-associated PNP who had recurrent corneal ulceration in addition to cicatrizing conjunctivitis. CASE PRESENTATION:We describe a case of 2...

journal_title：BMC ophthalmology

authors： Gong H,Zhou S,Hu Y,Lan Y,Zeng H,Wang L,Liu Q,Wang M

更新日期：2016-07-12 00:00:00

abstract：BACKGROUND:To understand the clinical and economic outcomes of treatments for managing complications of ischemic central retinal vein occlusion (iCRVO). METHODS:We conducted a systematic literature review by searching multiple databases and ophthalmology conferences from 2004 to 2015. Studies published in English lang...

journal_title：BMC ophthalmology

authors： Bradshaw SE,Gala S,Nanavaty M,Shah A,Mwamburi M,Kefalas P

更新日期：2016-07-11 00:00:00

abstract：BACKGROUND:The SRK/T formula is one of the third generation IOL calculation formulas. The purpose of this study was to evaluate the performance of the SRK/T formula in predicting a target refraction ±1.0D in short and long eyes using ultrasound biometry after phacoemulsification. METHODS:The present study was a retros...

journal_title：BMC ophthalmology

authors： Karabela Y,Eliacik M,Kaya F

更新日期：2016-07-08 00:00:00